World Class Outcomes & Exceptional Clinical Care.

With over 12,000 babies and counting, NYU Langone Fertility Center has been a world leader in providing compassionate and efficient fertility treatment since 1992.

Leading NYC Forward—One Family at a Time.

Join the thousands of families who've placed their trust in the experts at NYU Langone Fertility Center. When you're ready to explore your options, we're ready to help you build your family.

Comprehensive, Patient-Centered Fertility Care.

Our approach is simple: We’re in this together. We see patients for a full spectrum of fertility conditions, and our first job is to support our patients fully as they become educated about their options.

Your Future Family. Our Expert Team. Let’s Get Started.

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Industry Leading Experts

Join the thousands of families who've placed their trust in the experts at NYU Langone Fertility Center to deliver outstanding clinical outcomes and individualized fertility care.

Our team of doctors has over 125 years' collective experience performing IVF. Each physician is certified in Reproductive Endocrinology and Infertility (REI) with the American Board of Obstetrics and Gynecology, and many of our physicians also hold Professor or Assistant Professor positions within the Department of Obstetrics and Gynecology at NYU Langone Health. While they are physicians first and foremost, our doctors are also active participants in clinical research to advance the safety, success, and affordability of fertility treatments.

Meet The Team

James Grifo, M.D., PhD
Reproductive Endocrinologist & Infertility Specialist, Program Director
Scientific advancements have made it possible to dramatically improve pregnancy outcomes.

Alan S. Berkeley, M.D.

Reproductive Endocrinologist & Infertility Specialist

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Jennifer Blakemore, M.D., MSc

Reproductive Endocrinologist & Infertility Specialist

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Shannon DeVore, M.D.

Reproductive Endocrinologist & Infertility Specialist

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Elizabeth Fino, M.D.

Reproductive Endocrinologist & Infertility Specialist

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James A. Grifo, M.D., PhD

Reproductive Endocrinologist & Infertility Specialist, Program Director

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Brooke Hodes-Wertz, M.D., M.P.H

Reproductive Endocrinologist & Infertility Specialist

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David Keefe, M.D.

Reproductive Endocrinologist & Infertility Specialist

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Frederick L. Licciardi, M.D.

Reproductive Endocrinologist & Infertility Specialist

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Access to Care & Options for All

Whether you're just starting to explore fertility care or you're ready to start treatment, we're here to guide you through the many options you have to build your future family.

  • Fertility Health Screening
  • Intrauterine Insemination (IUI)
  • In Vitro Fertilization (IVF)
  • Fertility Preservation (“Egg Freezing”)
  • Fertility Preservation for Women with Cancer
  • Donor Egg & Third Party Reproduction Team
  • Surrogacy & Gestational Carriers
  • Preimplantation Genetic Testing (PGT)
  • Intracytoplasmic Sperm Injection (ICSI)
  • Sperm Freezing
  • Cryopreservation (Eggs & Embryos)

Fertility Health Screening

Learn about the health of your reproductive system by scheduling a  comprehensive fertility screening. This screening will include bloodwork to assess your Anti-Mullerian Hormone (“AMH”) and Follicle-Stimulating Hormone (“FSH”) levels, both of which are good indicators of your ovarian reserve. It will also include an ultrasound to evaluate your Antral Follicle Count (the number of follicles contained within your ovaries helps your physician to determine how many eggs may be produced in any given month) and a Semen Analysis (if appropriate).

NYU Langone Fertility Center provides state of the art fertility treatment and care in a compassionate, patient-focused environment. Depending upon the results of your fertility health screening, you may discuss many different options with your physician: clomid, IUI, IVF, PGT, the list goes on! Your physician will work with you to design a fertility plan that meets your needs.

Intrauterine Insemination (IUI)

Intrauterine insemination (IUI) is a relatively simple procedure that enables conception by directing sperm to the right place at the right time. In this process, a thin tube called a catheter is placed directly into the cervix, and a carefully prepared sperm sample is injected directly through the catheter into the uterus.

IUI increases the chances of becoming pregnant by injecting an optimal sperm sample directly into the uterus at a time when the woman is most fertile. Studies have shown that pregnancy is more likely to occur if timing of exposure to sperm is controlled in this way, and if sperm is placed in higher numbers closer to the egg or eggs.

When is IUI recommended? IUI is often recommended for women or couples who:

-Have been unsuccessful with infertility medications alone, or with other treatments

-Are unable to have appropriately timed intercourse due to travel distances, or in cases of sexual dysfunction

-Have unexplained infertility or mild male factor infertility

-Are women using donor sperm

In Vitro Fertilization (IVF)

In the course of a natural menstrual cycle, the brain produces hormones that stimulate one of the ovaries to release an egg. During an ovulation induction cycle, you are prescribed those same hormones, known as fertility medications, to stimulate the ovaries to mature numerous eggs at once. If more eggs are matured, more can be retrieved and used to create embryos. Most often, this improves the chances of fertilization, and ultimately pregnancy.

Around a month after the initial consultation, or when your targeted cycle starts, egg production will be stimulated with fertility medications. Frequent lab work and ultrasounds are done to monitor egg growth over the next 10–12 days. Then a final injection will be given to mature the eggs and prepare them for retrieval. Between 34-36 hours after the injection, the eggs will be retrieved under anesthesia. After the eggs are retrieved, they are evaluated; about three-quarters are generally considered mature enough for fertilization.

Approximately 18 hours after the egg and sperm were combined in the incubator, the embryology team evaluates the successful fertilization of each mature egg. If fertilization has indeed occurred, the embryology team monitors embryo development for an additional 2-4 days to assess embryo morphology (the shape and appearance of cells within the embryo).

There are two types of embryo transfer: fresh or frozen. In a fresh embryo transfer cycle, an embryo is transferred to the uterus after 3-5 days of observation in the embryology laboratory, and any additional embryos are frozen for future use. In a frozen embryo transfer (FET) cycle, all embryos are frozen after 3-5 days of development in the laboratory. If you wish to perform preimplantation genetic testing (PGT), embryos will be biopsied, then frozen while a culture of cells is sent to the genetic testing lab for analysis. Whether you proceed with a fresh embryo transfer or an FET, the embryo transfer process itself is very simple, and rarely requires sedation or anesthesia.

Fertility Preservation (“Egg Freezing”)

Egg freezing provides a great option for future family building—but it is truly the first step in a care continuum that may include egg thawing, embryo creation, embryo transfer, and attempted pregnancy. At NYULFC, our outcomes—from thousands of eggs safely frozen to hundreds of healthy babies born years later—speak to our expertise at each step.

Fertility Preservation for Women with Cancer

At NYU Langone Fertility Center, all of our physicians are experts in safeguarding the fertility of women battling complex medical diagnoses.

Over 250 women found to have a malignancy have chosen our Center to freeze their eggs or embryos. Amongst the women who have subsequently returned to thaw their eggs, 6 babies have been born to date, representing one of the largest single-center live birth reports for cancer survivors in the world.

At NYU Langone Fertility Center, we participate in the LIVESTRONG Fertility Discount Program and the Feering Pharmaceuticals Heart Beat Program to provide cost assistance for our patients battling a cancer diagnosis.

Donor Egg & Third Party Reproduction Team

At NYU Langone Fertility Center, your care team will include your physician, our Donor Egg & Third Party Reproduction specialists, an onsite psychologist, and nurses, coordinators, medical and administrative assistants, all of whom are here to help you navigate every step of your journey to parenthood using donor eggs and/or sperm.

  • Dr. Elizabeth Fino is the Director of the Donor Egg/Third Party Reproduction at NYU Langone Fertility Center.

Our dedicated team of Donor Egg support specialists includes:

  • Andria Besser, Genetic Counselor
  • Aleksandra Kostyra, RN, Donor Egg Program
  • Dr. Shelley S. Lee, PhD, Psychologist
  • Caroline McCaffrey, Lab Director
  • Nancy McGeoff, RN, Donor Egg Program
  • Jean Ann McKiernan, RN, Donor Egg Program
  • Dr. Mindy R. Schiffman, PhD, Psychologist
  • Alyssa Vargas, Donor Coordinator
  • Sylvia Wadowiec, Medical Secretary, Donor Gamete & Genetics

Surrogacy & Gestational Carriers

If you are unable to carry a pregnancy for any reason, the NYU Langone Fertility Center can work with you to identify a gestational surrogate to carry your baby.

A gestational surrogate is a woman who agrees to become pregnant by receiving an embryo transfer from an individual or couple who created an embryo using their own gametes ("autologous IVF"), donor eggs, donor sperm, or some combination of autologous and donor tissue.

Prior to any embryo transfer into a gestational surrogate, the U.S. Food and Drug Administration (FDA) mandates extensive screening for both the sperm and egg source, involving a questionnaire, physical exam, and blood tests. The gestational surrogate must also pass a physical and psychological examination.

In New York State, gestational surrogacy is only allowed on an altruistic, uncompensated basis. If an altruistic gestational carrier is not an option, we are happy to coordinate your cycle with our program affiliates at the New England Fertility Institute, in Stamford, Connecticut. Embryos can be created and frozen here at the NYU Langone Fertility Center, then sent to the New England Fertility Institute for embryo transfer to the selected gestational carrier.

To learn more about coordinating a gestational surrogacy cycle, please contact our Third Party Coordinator, Alyssa Vargas, via phone via phone at 212-263-0011 or via email at Alyssa.Vargas@nyulangone.org.

Preimplantation Genetic Testing (PGT)

Preimplantation genetic testing for aneuploidy (PGT-A) allows us to count the number of chromosomes in an embryo biopsy. A euploid or “normal” embryo contains 23 pairs of chromosomes, though abnormalities in chromosome number (i.e. too many or too few, or structural defects) are common and their incidence increases as women age. In some cases, these abnormalities can lead to miscarriage and other health concerns. PGT-A testing reduces the risk of miscarriage by reducing the chance of transferring a genetically abnormal embryo.

For patients with specific inherited genetic or chromosomal conditions that may impact a pregnancy, preimplantation genetic testing for monogenetic disorders (PGT-M) or structural rearrangements (PGT-SR) may be considered. These tests use customized approaches, tailored to identify specific genetic variants (mutations) or chromosomal imbalances ahead of implantation, ultimately increasing the chance of a successful pregnancy.

Intracytoplasmic Sperm Injection (ICSI)

In most cases at NYU Langone Fertility Center, sperm are combined with the eggs and fertilization occurs naturally. In situations where low sperm count or low sperm motility (movement) is a factor, a single sperm is injected directly into each mature egg in a process called intracytoplasmic sperm injection (ICSI).

In standard (non-ICSI) IVF, about 50,000 sperm are added to each egg in a petri dish, allowing the sperm to penetrate the eggs "naturally." In cases where the sperm are unable to fertilize the egg on their own, the embryologist can employ ICSI to inject the sperm directly into the egg. If a sperm sample is considered 'borderline,' some eggs may be injected while others are given the chance to fertilize naturally in the petri dish.

In cases that require ICSI, the male partner provides a sperm sample (this usually occurs on the same day as the egg retrieval procedure; however samples can be collected in advance and stored frozen until needed). An embryologist analyzes the sample and isolates the strongest and best swimming (motile) sperm to be used for insemination. To perform ICSI, each egg is held by gentle suction in a glass pipette, and a single sperm is injected through the zona (shell) of the egg using a tiny, glass microneedle. The sperm is deposited deep into the innermost part of the egg (cytoplasm) and the needle is withdrawn.

Sperm Freezing

Sperm freezing preserves sperm now for use later, giving patients the opportunity to build a family when the time is right.

Through a process called cryopreservation, you can preserve your sperm until needed for assisted reproductive procedures such as IVF (in vitro fertilization), IUI (intrauterine insemination), or sperm donation.

If you are considering undergoing a medical procedure that may put your reproductive health at risk, it may be a good idea to consider preserving your sperm. Some common interventions that may put you at risk include chemotherapy, pharmaceuticals, and vasectomies. Sperm banking may also be a good idea if you are in a profession that puts your fertility at risk.

Cryopreservation (Eggs & Embryos)

The cryopreservation of eggs or embryos begins with “vitrification” or “freezing.” Vitrification is an ultra-rapid freezing process performed in our embryology laboratory, wherein the eggs/embryos are rapidly cooled to subzero temperatures. This rapid cooling process prevents the formation of ice crystals, which can cause cell damage.

The process of vitrification has three critical components. First, eggs/embryos are exposed to high concentrations of cryoprotectants to allow rapid dehydration of cells. Second, the eggs/embryos are loaded into tiny storage devices (usually straws) that will facilitate ultra-rapid cooling. Third, the straws containing the eggs/embryos are cooled as fast as possible, typically at thousands of degrees per minute.

In practice, this means that eggs and embryos are vitrified very quickly in the laboratory. A typical embryo vitrification protocol is complete in about 10 minutes. Embryos are removed from the incubator in the laboratory and exposed to an equilibration solution for 8 minutes to begin the dehydration process. After 8 minutes in equilibration solution, the embryos are moved into a vitrification solution for 60 seconds. Then, they are quickly loaded into straws and plunged into liquid nitrogen at a temperature of -196°C. The tiny straw will cool from room temperature (about 25°C) to -196°C in two to three seconds, giving a cooling rate of 4420-6630°C per minute.

This high cooling rate combined with the use of high concentrations of cryoprotectants allows the contents of the straw (embryos plus surrounding fluid) to turn to a glass like substance instead of ice. Avoiding ice formation in this way successfully protects the embryos from damage and allows them to be warmed later giving survival rates consistently above 90%.

For egg vitrification, the process is similar, but the exposure to the equilibration solution is slower, usually about 15 minutes, and it is broken up into 4 steps. This stepwise approach is designed specifically for the egg and achieves the same level of dehydration as can be obtained with embryos in a shorter time. These steps, however, are critical to the survival of the eggs and must be followed exactly. Moving the eggs into vitrification solution, loading and cooling the straws is the same as is done for embryos.

This high cooling rate, combined with the use of of cryoprotectants, allows the contents of the straw (embryos plus surrounding fluid) to turn into a glass-like substance instead of ice. Avoiding ice formation in this way successfully protects the embryos from damage and allows them to be warmed later, delivering embryo survival rates consistently above 90%.

When our patients return to use their vitrified embryos, the vitrification procedure described above is reversed to allow warming back to room temperature for rehydration. The procedure "warms" the tissue in just 20 minutes, and it is placed back in the incubator at 37°C in the laboratory. Embryos can be transferred back to the uterus immediately and eggs can be fertilized with sperm 3-4 hours later.

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NYULFC IVF Patient

I truly felt that we came up with our fertility plan together, which helped make me feel more involved and in control.

Our doctor spent a ton of time with us during our consultation. He was straightforward, but also very positive. He really seemed interested in getting to know us as a couple, and he explained our test results to us in ways we could understand. He was thorough in the tests he recommended, and always told us his expert opinion, not just what we wanted to hear. I truly felt that we came up with our fertility plan together, which helped make me feel more involved and in control.

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NYULFC Egg Freezing Patient

I never imagined fertility preservation would be part of my plan, much less an empowering process in my fertility journey.

It’s a decision I have no regrets about making, and I encourage others to explore this option for themselves.

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NYULFC Donor Egg Recipient

When people find out about my children, they ask, ‘Did you have help? Are they natural?’

Of course they’re natural. I like the idea of destigmatizing the process behind helping people make families—every baby is natural.

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NYULFC Egg Donor

I felt so lucky to work with the NYU Langone Fertility Center donor egg team.

Not only are they perhaps the most advanced and forward-thinking fertility specialists, but they also exhibited incredible empathy throughout my donation process. Everyone was upbeat, straightforward, and caring at every step.

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NYULFC LGBTQ Family

The doctors and nurses we’ve been working with have been amazing in cultivating mindfulness and understanding.

They answer all our questions (and there are a lot of them), but they’re able to do it without being overwhelming. There are so many steps in this process—it’s incredibly comforting to have such a genuinely supportive team helping us build our family.

Questions? Talk to Us.

We're here to go at your pace and answer any questions you have.

Get in touch when you're ready. We'll be right here.